Higher lung cancer rates have been reported in people with HIV/AIDS than in the general population, but it has not been clear why.
To find an answer, researchers at the University of California at San Francisco sought to determine the incidence and risk factors for lung cancer among women and men in 2 longitudinal studies of HIV infection in the United States. Results were announced here at the 13th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICMAOI) at the National Institutes of Health.
The researchers hypothesized that the increased incidence of lung cancer among HIV-infected people was primarily due to cigarette smoking and secondarily to preexisting lung disease.
HIV infection was not associated with lung cancer in a sample of women and was no longer significant in a sample of men after adjustment for prior AIDS diagnosis, according to Nancy Hessol, MSPH, professor in the departments of clinical pharmacy and medicine at the University of California at San Francisco, who reported findings from the Women's Interagency HIV Study (WIHS) and Men in the Multicenter AIDS Cohort Study (MACS).
Complete article at Medscape : http://bit.ly/rzxRjj