A possible step to better HIV treatment is a new class of compounds that stick to the coating of the virus and can stop it from infecting cells, , U.S. researchers say.
University of Utah scientists say the compound can act as a microbiocide by attaching to the sugary coating of the human immunodeficiency virus that causes AIDS to prevent it from entering the cells of a host organism and taking control of the cells' replication machinery to make copies of itself, a university release said Friday.
Those two steps of the HIV life cycle, known as viral entry and viral replication, can each be a potential target for anti-HIV medicines, researchers said.
"Most of the anti-HIV drugs in clinical trials target the machinery involved in viral replication," senior author Patrick F. Kiser, Utah State professor of bioengineering and pharmaceutical chemistry, said.
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